Job Description Job Title: Senior Lecturer/Senior Study Manager for Oncology Posting Start Date: 27/03/2026 Job Id: 2447 School/Department: School of Medicine & Population Health Work Arrangement: Full Time (Hybrid) Contract Type: Permanent Salary per annum (£): 61,759-69,488 Closing Date: 24/04/2026

The University of Sheffield is a remarkable place to work. Our people are at the heart of everything we do. Their diverse backgrounds, abilities and beliefs make Sheffield a world-class university.

We offer a fantastic range of benefits including a highly competitive annual leave entitlement (with the ability to purchase more), a generous pensions scheme, flexible working opportunities, a commitment to your development and wellbeing, a wide range of retail discounts, and much more.

Overview
A position has arisen for a Senior Lecturer/Senior Study Manager for Oncology based in the Sheffield Clinical Trials Research Unit (CTRU). Sheffield CTRU has received substantial infrastructure funding to grow and diversify its portfolio of multi-centre cancer clinical trials . The post holder will be responsible for trial design, grant development, and submission, as well as oversight of Quality Assurance and senior-level study implementation, with a specific focus on oncology-based CTIMPs (Clinical Trials of Investigational Medicinal Products). You will work closely with the CTRU Academic Lead for Oncology, CTRU staff and Chief Investigators to secure research funding and ensure that studies under your supervision are implemented in accordance with randomised controlled trial scientific principles, the study protocols, and regulatory standards. You will provide oversight of all CTRU input into the specialist oncology studies within your portfolio, ensuring that all services provided by the Unit are compliant with professional, national, and international regulatory frameworks. Experience of project-managing large, multi-centre cancer clinical trials is essential. We are seeking a candidate with a proven track record of working within the oncology research field , possessing a deep understanding of the Medicines for Human Use (Clinical Trials) Regulations as they apply to complex cancer research.
Main duties and responsibilities You will be responsible for:

Support the Director of the Sheffield Clinical Trials Research Unit and the Academic Lead for Oncology Trials in the overall management and strategic delivery of the infrastructure grant, ensuring that the project meets its key milestones and deliverables.
Developing a specialist portfolio of oncology research in collaboration with clinical investigators through designing studies, submitting research applications, and securing grants.
Acting as the senior CTRU representative (CTRU Lead) for studies, liaising with oncology Chief Investigators, clinicians , research collaborators, and methodologists.
Ensuring the cancer research studies for which you are the CTRU lead are undertaken in accordance with randomised controlled trial scientific principles and the protocol.
Overseeing all CTRU input into the oncology portfolio for which you are the CTRU lead.
Supervision of trial managers, particularly managers of oncology CTIMP studies .
Overseeing Quality Assurance processes within the Oncology portfolio.
Under your supervision, ensuring that regulatory standards and specialized oncology pharmacovigilance procedures (including reporting of complex Adverse Events common in cancer trials) on all CTRU CTIMPs are adhered to.
Under your supervision, ensuring compliance with research ethics, the Medicines for Human Use Clinical Trials Regulations (2004) , clinical governance, data protection, and Good Clinical Practice (GCP) requirements.
If required, lead on preparation for and response to (Medicines and Healthcare products Regulatory Agency) MHRA inspections , specifically regarding the oncology portfolio.
Lead on the preparation of papers for high-impact oncology and academic journals .
Lead on the presentation of findings at international cancer conferences and academic forums .
Hold responsibility for delivery of studies within agreed timescales and funding.
Undertake undergraduate and post-graduate teaching and supervision, within the School of Medicine and Population Health.
Undertake post-graduate research supervision and examining as required.
You will make a full and active contribution to the principles of the ‘Sheffield Academic’. These include the achievement of excellence in applied teaching and research, and scholarly pursuits to make a genuine difference in the subject area and to the University’s achievements as a whole.
As a member of staff, you will be encouraged to make ethical decisions in your role, embedding the University sustainability strategy into your working activities wherever possible.
Any other duties, commensurate with the grade of the post.

Person Specification Our diverse community of staff and students recognises the unique abilities, backgrounds, and beliefs of all. We foster a culture where everyone feels they belong and is respected. Even if your past experience doesn't match perfectly with this role's criteria, your contribution is valuable, and we encourage you to apply. Please ensure that you reference the application criteria in the application statement when you apply.
Criteria
Essential or desirable
Stage(s) assessed at
Academic Qualifications: Postgraduate qualification in a relevant health-related or methodological area.
Essential
Application/interview
Oncology Research Expertise: Extensive experience in health services or clinical research specifically within the oncology field, with a deep understanding of cancer-specific trial complexities.
Essential
Application/interview
Trial Methodology: Sound understanding of the scientific principles of RCTs, including experience with innovative/adaptive trial designs (e.g., basket or platform trials) relevant to precision medicine.
Essential
Application/interview
Project Management: Proven track record of project managing large, multi-site, multi-centre oncology trials from setup to close-out.
Essential
Application/interview
Regulatory Mastery: Advanced experience working on Oncology CTIMPs and thorough knowledge of The Medicines for Human Use (Clinical Trials) Regulations 2004 and ICH Good Clinical Practice (GCP).
Essential
Application/interview
Grant Development & Income: Extensive experience collaborating with senior clinical investigators to design, develop, and successfully secure major research grants (e.g., NIHR, CRUK, MRC or major charities).
Essential
Application/interview
Quality & Inspection: Experience taking a lead responsibility for Quality Assurance or playing a significant role in MHRA inspections within a Clinical Trials Unit environment.
Essential
Application/interview
Inclusivity & EDI: Knowledge or experience of applying frameworks (e.g., INCLUDE) to improve trial participation among underserved or socioeconomically disadvantaged populations.
Desirable
Application/interview
Academic Output: A strong track record of high-quality, peer-reviewed clinical research papers published in high-impact oncology or medical journals.
Essential
Application/interview
Leadership & Mentorship: Experience in supervising Trial Managers and mentoring early-career researchers or clinical fellows (e.g., NHS Consultants/AHPs) in trial development.
Essential
Application/interview
Communication & Stakeholder Engagement: Excellent skills in maintaining relationships with Chief Investigators, trial funders, and Cancer Patient and Public Involvement (PPI) panels.
Essential
Application/interview
Strategic Problem Solving: Ability to develop creative approaches to complex trial problems (e.g., recruitment barriers in oncology) with an appreciation for long-term sustainability and strategic aims.
Essential
Application/interview
Further Information
Grade
Grade 9
Salary
£61,759-69,488

Potential to progress to £80,524 per annum through sustained exceptional contribution.

Work arrangement
Full-time / Part-time (a minimum of 0.6FTE)
Hybrid working with a minimum of 60% of working days are expected to be undertaken on site, to be agreed with the successful candidate.
Duration
Permanent
Line manager
CTRU Academic Lead for Oncology Trials
Direct reports

Trial Manager
Study Managers
Study Delivery Staff

Our website
https://sheffield.ac.uk/ctru
For informal enquiries about this job contact Prof Matt Hammond, Director of the Sheffield Clinical Trials Research Unit: on

Next steps in the recruitment process It is anticipated that the selection process will take place in May. This will consist of a 10 minute presentation and subsequent interview. If you need any support, equipment or adjustments to enable you to participate in any element of the recruitment process you can contact .
Our vision and strategic plan We are the University of Sheffield. This is our vision: sheffield.ac.uk/vision. What we offer

A minimum of 41 days annual leave including bank holiday and closure days (pro rata) with the ability to purchase more.
Flexible working opportunities, including hybrid working for some roles.
Generous pension scheme.
A wide range of discounts and rewards on shopping, eating out and travel.
A variety of staff networks, providing opportunities for social interaction, peer support and personal development (for example, Race Equality, LGBT+, Women’s and Parent’s networks).
Recognition Awards to reward staff who go above and beyond in their role.
A commitment to your development access to learning and mentoring schemes; integrated with our Academic Career Pathways
A range of generous family-friendly policies
- paid time off for parenting and caring emergencies
- support for those going through the menopause
- paid time off and support for fertility treatment
- and more

We are a Disability Confident Employer. If you have a disability and meet the essential criteria for this job you will be invited to take part in the next stage of the selection process.

Closing Date : 24/04/2026

We are a research university with a global reputation for excellence. Our ideas and expertise change the world for the better, making a real difference to society. We know that when people come together with different views, approaches and insights it can lead to richer, more creative and innovative teaching and research and the highest levels of student experience. Our University Vision (www.sheffield.ac.uk/vision) outlines our commitment to building a diverse community of staff and students that recognises and values the abilities, backgrounds, beliefs and ways of living for everyone.

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Senior Lecturer/Senior Study Manager for Oncology